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  • Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(iv) as models for biological redox systems.

Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(iv) as models for biological redox systems.

Dalton transactions (Cambridge, England : 2003) (2017-06-18)
Jingran Dong, Yanli Ren, Sufang Sun, Jiao Yang, Chunxia Nan, Hongmei Shi, Jianzhong Xu, Jie Duan, Tiesheng Shi, Lars I Elding
RESUMEN

A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl

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Sigma-Aldrich
Perclorato de sodio, ACS reagent, ≥98.0%
Sigma-Aldrich
Sodium hexachloroiridate(IV) hexahydrate, 99.9% trace metals basis