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Key Documents

1269254

USP

Famotidine Related Compound E

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

N,N′′′-[Dithiobis(methylene-4,2-thiazolediyl)]bisguanidine, 2,2′-[4,4′-Disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguanidine

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About This Item

Fórmula empírica (notación de Hill):
C10H14N8S4
Número de CAS:
Peso molecular:
374.53
UNSPSC Code:
41116107
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

USP

API family

famotidine

form

powder

packaging

pkg of 25 mg

manufacturer/tradename

USP

storage condition

protect from light

color

white

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C10H14N8S4/c11-7(12)17-9-15-5(1-19-9)3-21-22-4-6-2-20-10(16-6)18-8(13)14/h1-2H,3-4H2,(H4,11,12,15,17)(H4,13,14,16,18)

InChI key

ZWHJVLVEEDAPHN-UHFFFAOYSA-N

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General description

Famotidine Related Compound E (Famotidine Impurity E) is an impurity of famotidine, which is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Famotidine Related Compound E can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by various analytical techniques.
Also, for use with USP monograph such as Famotidine

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Famotidine
Pharmacopeia, US
United States Pharmacopeia, 39(1)(1-2), 1815-1815 (2020)
RP-HPLC determination of famotidine and its potential impurities in pharmaceuticals
Helali N, et al.
Chromatographia, 60(7-8) (2004)
Potentiometric determination of famotidine in pharmaceutical formulations
Ayad MM, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(1-2) (2002)
Photoaffinity labeling of the anionic sites in Caco-2 cells mediating saturable transport of hydrophilic cations ranitidine and famotidine
Bourdet DL, et al.
Journal of medicinal chemistry, 47(11) (2004)

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