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Key Documents

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S2067

Sigma-Aldrich

S9 from Liver, Pooled

from rat(Sprague-Dawley), male

Sinónimos:

Liver S9 Fraction, S9 Liver Extract

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About This Item

UNSPSC Code:
12161501
NACRES:
NA.47

biological source

rat (Sprague-Dawley)

Quality Level

200

packaging

vial of ~20 mg

UniProt accession no.

B0BN68

shipped in

dry ice

storage temp.

−70°C

Gene Information

rat ... Mrps9(301371)

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Application

S9 from Liver, Pooled has been used in metabolic activation in Salmonella typhimurium strains.

Biochem/physiol Actions

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Glucose-6-phosphate mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

Roche

10127647001

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Sigma-Aldrich

A55500

2-Aminofluorene

NADP Disodium salt

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NADP-RO

NADP

Genotoxicity evaluation of locally produced dental porcelain-An in vitro study using the Ames and Comet assays
Noushad M, et al.
Toxicology in vitro, 23(6), 1145-1150 (2009)
The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
Esra Erikel et al.
Environmental and molecular mutagenesis, 64(5), 291-308 (2023-05-10)
Amygdalin (AMY), a plant secondary metabolite containing nitrile, is a major component of the seeds of Rosaceae family plants. It is known that this compound has many pharmacological activities such as cancer prevention, antipyretic, and cough suppressant. In this study
Milena Lopes Francisco Bittencourt et al.
Life sciences, 256, 117977-117977 (2020-07-01)
Silibinin is the major component of flavonolignans complex mixture (Silymarin), which is obtained from Silybum marianum (L.) Gaertn. Despite several reports about silibinin, little is known about its effects on gastric diseases. Then, the present study aims to evaluate the
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Toxicology research, 10(3), 511-522 (2021-06-19)
The titanium dioxide nanoparticles (NPs) have been applied to biomedical, pharmaceutical, and food additive fields. However, the effect on health and the environment are conflicting; thus, it has been reviewing several times. In this context, establishing standard robust protocols for
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