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Merck

46036

Supelco

Brodifacoum

PESTANAL®, analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C31H23BrO3
Número de CAS:
Peso molecular:
523.42
Beilstein/REAXYS Number:
8171403
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccc(Br)cc5)C(=O)Oc6ccccc16

InChI

1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

InChI key

VEUZZDOCACZPRY-UHFFFAOYSA-N

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General description

Brodifacoum is an anticoagulant rodenticide, widely used for the control of rodent population via inhibition of the vitamin K epoxide reductase, causing blood clotting alterations, leading to haemorrhaging as the ultimate cause of death.

Application

Brodifacoum may be used as an analytical reference standard for the quantification of the analyte in animal samples and biological samples using different chromatography techniques..
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - STOT RE 1

target_organs

Blood

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificados de análisis (COA)

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1 of 5

The determination of the anticoagulant rodenticide brodifacoum in blood serum by liquid chromatography with fluorescence detection
Felice.JL and Murphy.JM
Journal of Analytical Toxicology, 13(4), 229-231 (1989)
Reversed-phase HPLC determination of eight anticoagulant rodenticides in animal liver
Fauconnet.V, et al.
Journal of Analytical Toxicology, 21(7), 548-553 (1997)
Manifestations of superwarfarin ingestion: a plea to increase awareness.
Dipika Misra et al.
American journal of hematology, 85(5), 391-392 (2010-03-17)
Kaylin S Watson et al.
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 164(2), 70-72 (2012-06-13)
Superwarfarin vitamin K antagonists are found in rat poisons and are readily available. Pediatric exposures are common but are usually asymptomatic without significant coagulopathy. Superwarfarin intoxication must be considered in any adult who presents with an unexplained coagulopathy with extreme
Alan P Buckle et al.
Pest management science, 68(12), 1579-1585 (2012-09-26)
The tyrosine to cysteine amino acid substitution at location 139 of the vkorc1 protein (i.e. tyrosine139cysteine or Y139C) is the most widespread anticoagulant resistance mutation in Norway rats (Rattus norvegicus Berk.) in Europe. Field trials were conducted to determine the

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