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Key Documents

567028

Sigma-Aldrich

SIN-1 hydrochloride

≥98% (HPLC), solid, nitric oxide (NO) donor, Calbiochem®

Sinónimos:

SIN-1, Hydrochloride, 3-Morpholinosydnonimine, HCl

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About This Item

Fórmula empírica (notación de Hill):
C6H10N4O2 · xHCl
Número de CAS:
16142-27-1
Peso molecular:
170.17 (free base basis)
MDL number:
MFCD00214332
UNSPSC Code:
12352200
NACRES:
NA.77

product name

SIN-1, Hydrochloride, Nitric oxide (NO) donor.

Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

DMSO: 10 mg/mL
ethanol: 10 mg/mL
water: 25 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1

InChI key

ZRFWHHCXSSACAW-UHFFFAOYSA-M

General description

Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets.
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets. Unstable in aqueous solution.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Unstable in aqueous solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).





From Catalog:

Desc. Field- added "Unstable in aqueous solution."

Other Notes

Gow, A.J., et al. 2000. Am. J. Physiol. 278, C1099.
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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