Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

4060

Millipore

Inosine

A metabolite of adenosine that acts as a potent coronary vasodilator. Exhibits a positive inotropic action on heart muscle and can antagonize the ouabain-induced arrhythmias.

Sinónimos:

Inosine, Hypoxanthine Riboside

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C10H12N4O5
Número de CAS:
58-63-9
Peso molecular:
268.23
MDL number:
MFCD00066770
UNSPSC Code:
12352208
NACRES:
NA.51

Quality Level

100

assay

≥99% (by assay)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: soluble

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)

InChI key

UGQMRVRMYYASKQ-UHFFFAOYSA-N

General description

A metabolite of adenosine that acts as a potent coronary vasodilator. Exhibits a positive inotropic action on heart muscle and can antagonize the ouabain-induced arrhythmias.
Correlates well with myocardial contractile performance.

Warning

Toxicity: Standard Handling (A)

Other Notes

Aviado, D.M. 1983. J. Pharmacol. 14 (suppl. 3), 47.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Juan M Roldan-Romero et al.
International journal of cancer, 146(5), 1435-1444 (2019-07-25)
The mammalian target of rapamycin (mTOR) pathway inhibitors are key drugs for the treatment of many tumor types, however, there are no predictive biomarkers in clinical use. Here, we performed a molecular and immunohistochemical characterization of key mTOR pathway components
Hsiao-Chun Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(5), 1813-1824 (2018-09-20)
Acupuncture involves inserting a fine needle into a specific point, often called an acupoint, thereby initiating a therapeutic effect accompanied by phenomena such as soreness, heaviness, fullness, and numbness. Acupoints are characterized as points located in deep tissues with abundant
Heejung Yang et al.
Planta medica, 79(1), 78-82 (2012-11-17)
Bioassay-guided fractionation of an 80% methanolic extract of Salix pseudo-lasiogyne twigs has resulted in the isolation of two new compounds (1-2) along with ten known ones (3-12). The new compounds were determined to be 3'-O-acetylsalicin (1) and 2',6'-O-acetylsalicortin (2) by
Srinivasa Rao Bolla et al.
Heliyon, 5(5), e01648-e01648 (2019-06-14)
Identification and assessment of therapeutic potential of natural products derived from medicinal plants have led to the discovery of innovative and economical drugs to treat several diseases, including chronic wounds. In vitro cell based scratch assay is an appropriate and
Kyoung-Mi Park et al.
American journal of physiology. Heart and circulatory physiology, 311(2), H371-H383 (2016-06-12)
The nonselective β-adrenergic receptor antagonist (β-blocker) carvedilol has been shown to protect against myocardial injury, but the detailed underlying mechanisms are unclear. We recently reported that carvedilol stimulates the processing of microRNA (miR)-199a-3p and miR-214 in the heart via β-arrestin1-biased
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico