19-123-M
Staurosporine
Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases.
Sinónimos:
PKC inhibitor, protein kinase C inhibitor
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About This Item
Código UNSPSC:
12352200
eCl@ss:
32160405
NACRES:
NA.41
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Descripción general
Suitable for use as a potent inhibitor of PKC and other protein kinases in vitro and in cultured cells.
Aplicación
Staurosporine has been used as a protein kinase inhibitor to study the ubiquitin-protein ligase E3 component N-recognin 5 (UBR5)-mediated CDC73 regulation at the protein level. Staurosporine has been used to induce apoptosis in CHO-K1 cell lines, followed by cell imaging and extraction of cell lysate for further analysis.
Acciones bioquímicas o fisiológicas
Staurosporine, a broad-spectrum protein kinase inhibitor, belongs to the indolocarbazole family. It is referred to as a prototypical ATP-competitive kinase inhibitor. Staurosporine is effective against various kinds of cancers. It is commonly used for inducing apoptosis in different types of cells.
Calidad
Routinely evaluated by Protein Kinase Inhibition Assay
Información legal
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Aquatic Chronic 4 - Repr. 2
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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