P-009

Pentobarbital-D₅ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₁₁D₅H₁₃N₂O₃
• Número de CAS: 52944-66-8
• Peso molecular: 231.30
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]C([2H])([2H])C([2H])([2H])C1(C(C)CCC)C(=O)NC(=O)NC1=O
• InChI: 1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)/i2D3,5D2
• InChI key: WEXRUCMBJFQVBZ-ZTIZGVCASA-N

Descripción

General description

A stable-labeled internal standard suitable for pentobarbital testing by GC/MS or LC/MS for clinical toxicology, forensic analysis, or urine drug testing applications. Pentobarbital is a short-acting barbiturate and hypnotic sold under the trade name Nembutal^® and approved for treatment of seizures and preoperative sedation. Also known as pentobarbitone, the sodium salt of pentobarbital is used as an anesthetic in veterinary medicine.

Application

• Pentobarbital-D₅ as a reference standard in therapeutic drug monitoring: Pentobarbital-D₅ is utilized as a stable isotope-labeled internal standard in the quantitative determination of drugs, including statins, by high-resolution tandem mass spectrometry. This application is critical for adherence testing and therapeutic drug monitoring, ensuring precise and reliable measurement in biochemical research (Wagmann et al., 2020).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Nembutal is a registered trademark of Oak Pharmaceuticals, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup