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C-130

Supelco

Cortisone solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C21H28O5
Número de CAS:
53-06-5
Peso molecular:
360.44
Número CE:
200-659-6
Número MDL:
MFCD00003610
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material

Formulario

liquid

Características

(Snap-N-Spike®)

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

100 μg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

clinical testing
clinical testing

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4CC3)C)C(=O)C2)CC1)C)C(=O)CO

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

Clave InChI

MFYSYFVPBJMHGN-ZPOLXVRWSA-N

Descripción general

Cortisone is a corticosteroid produced in the adrenal glands. Cortisone is administered for short term pain relief and to reduce swelling from inflammation. This Certified Spiking Solution® is applicable in LC-MS/MS applications for endocrinology, clinical chemistry and neonatal screening.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number

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Hanns Kaiser
Wiener klinische Wochenschrift, 115(1-2), 6-21 (2003-03-28)
Five decades of experimental and clinical experience have changed corticoid therapy thoroughly. Corticoides have two modes of action. The first is a genomic effect through which anti-inflammatory proteins are formed which inhibit pro-inflammatory cytokines. This effect is initiated even by
[From classical corticotherapy to cortisone loading].
J Arlet
Annales de medecine interne, 145 Suppl 2, 5-10 (1994-06-01)
[50 years cortisone treatment--what has changed?].
H Kaiser
Fortschritte der Medizin, 116(26), 20-22 (1998-11-17)
P M Stewart et al.
Steroids, 58(12), 614-620 (1993-12-01)
The role of adrenal steroid hormones in hypertension has, until recently, focused on disorders of secretion. We describe a new form of mineralocorticoid hypertension which arises from impaired metabolism of physiological glucocorticoid. 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) is responsible for
[Cortisone substitution in sepsis. Is less more?].
J Briegel
Der Anaesthesist, 52 Suppl 1, S24-S31 (2004-01-17)
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