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308021

Sigma-Aldrich

3-Hydroxyphthalic anhydride

98%

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About This Item

Fórmula empírica (notación de Hill):
C8H4O4
Número de CAS:
37418-88-5
Peso molecular:
164.11
Beilstein/REAXYS Number:
135783
MDL number:
MFCD00011557
UNSPSC Code:
12162002
PubChem Substance ID:
24858644
NACRES:
NA.23

assay

98%

form

solid

mp

199-202 °C (lit.)

SMILES string

Oc1cccc2C(=O)OC(=O)c12

InChI

1S/C8H4O4/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3,9H

InChI key

CCTOEAMRIIXGDJ-UHFFFAOYSA-N

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Categorías relacionadas

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

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3-Nitrophthalic acid 95%

Sigma-Aldrich

369306

3-Nitrophthalic acid

Phthalic anhydride ACS reagent, ≥99%

Sigma-Aldrich

320064

Phthalic anhydride

tert-Butyl bromoacetate 98%

Sigma-Aldrich

124230

tert-Butyl bromoacetate

Lin Li et al.
Journal of acquired immune deficiency syndromes (1999), 56(5), 384-392 (2011-01-18)
The development of a safe, effective, and affordable microbicide to prevent the sexual transmission of HIV combination is urgently needed. Our previous studies demonstrated that 3-hydroxyphthalic anhydride-modified chicken ovalbumin (HP-OVA) exhibited potent antiviral activity against a broad spectrum of HIV
Lin Li et al.
The Journal of antimicrobial chemotherapy, 68(3), 573-576 (2012-12-12)
We recently demonstrated that both 3-hydroxyphthalic anhydride (HP)- and maleic anhydride-modified chicken ovalbumin (OVA) could effectively inhibit HIV-1 infection. But because OVA may cause allergy in some human subjects, here we replaced OVA with human serum albumin (HSA) in designing
Li-li He et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 31(7), 1175-1178 (2011-07-19)
To investigate the antiviral activity of 3-hydroxyphthalic anhydride-modified ovalbumin (HP-OVA) against herpes simplex virus 2 (HSV-2) in vitro. By chemical modification, ovalbumin (OVA) was treated with 3-hydroxyphthalic anhydride (HP) to prepare HP-OVA. The anti-HSV-2 activity against HSV-2 333 virus in
Lin Li et al.
Antimicrobial agents and chemotherapy, 54(5), 1700-1711 (2010-03-03)
Heterosexual transmission is the primary route by which women acquire human immunodeficiency virus (HIV)/AIDS. Thus, development of woman-controlled topical microbicides for prevention of sexual transmission of HIV is urgently needed. Here we report that 3-hydroxyphthalic anhydride-modified chicken ovalbumin (HP-OVA) exhibits
Youming Shen et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 185, 371-375 (2017-06-12)
A new turn-on phthalimide fluorescent probe has designed and synthesized for sensing cysteine (Cys) based on excited state intramolecular proton transfer (ESIPT) process. It is consisted of a 3-hydroxyphthalimide derivative moiety as the fluorophore and an acrylic ester group as
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