SAB5600004

Anti-Mouse IgG2c antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM223, purified immunoglobulin

• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• recombinant: expressed in HEK 293 cells
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: RM223, monoclonal; recombinant monoclonal
• form: buffered aqueous glycerol solution
• species reactivity: mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 0.01 μg/mL; immunoblotting: 0.5-2 μg/mL (non-reduced only); immunocytochemistry: 0.5-2 μg/mL; immunohistochemistry: 0.5-2 μg/mL
• isotype: IgG
• NCBI accession no.: 404711
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Description

General description

IgG2c codes for Igh-1b. In mice, IgG2a and IgG2c are arranged in tandem on identical chromosome as two visible loci.

Specificity

This antibody reacts to the Fc region of mouse IgG2c. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG3, IgM, IgA, IgE, human IgG, or rat IgG.

Immunogen

Purified mouse IgG2c whole molecule

Biochem/physiol Actions

Mouse IgG2c generate several unique non-bonded interactions between the BC, DE and FG loops than mIgG2b. It connects to FcγRIV (Fc γ receptor IV) with a high affinity in the complex-type glycoform. In mice, IgG2c has unique immune profiles like, response, immune-decoration, because of their difference in protein sequence.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable