ABN292

Anti-DDAH2 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): N(G),N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase protein
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• species reactivity (predicted by homology): bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI accession no.: NP_039268
• UniProt accession no.: O95865
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... DDAH2(23564)

Description

General description

Dimethylarginine dimethylaminohydrolase 2 (DDAH2) is also called N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2), DDAHII, Dimethylargininase-2, Protein G6a and S-phase protein. DDAH2 is involved in nitric oxide generation through the hydrolyzation of N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which are NOS inhibitors. DDAH2 is expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human DDAH2.

Application

Detect Dimethylarginine dimethylaminohydrolase 2 using this rabbit polyclonal antibody, Anti-DDAH2 Antibody validated for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected DDAH2 in human kidney and human cardiac myocytes tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected DDAH2 in 10 µg of human heart tissue lysate.

Target description

~36 kDa observed. Uncharacterized band(s) may appear in some lysates.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable