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M5760

Sigma-Aldrich

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

>97.5% purity (HPLC), powder

Synonym(s):

4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole, MBD

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About This Item

Empirical Formula (Hill Notation):
C14H12N4O4
CAS Number:
Molecular Weight:
300.27
Beilstein:
1151390
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan,

Assay

>97.5% (HPLC)

form

powder

color

orange to red

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

COc1ccc(CNc2ccc([N+]([O-])=O)c3nonc23)cc1

InChI

1S/C14H12N4O4/c1-21-10-4-2-9(3-5-10)8-15-11-6-7-12(18(19)20)14-13(11)16-22-17-14/h2-7,15H,8H2,1H3

InChI key

IENONFJSMWUIQQ-UHFFFAOYSA-N

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Application

Fluorescent probe for hydrophobic (non-polar) regions in proteins and nucleoproteins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Angharad R Morgan et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 15(6), 776-787 (2019-05-03)
Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. A hypothesis-led plasma biomarker search was conducted in the context of international multicenter studies. The discovery
Andaine Seguin-Orlando et al.
Scientific reports, 5, 11826-11826 (2015-07-03)
The recent discovery that DNA methylation survives in fossil material provides an opportunity for novel molecular approaches in palaeogenomics. Here, we apply to ancient DNA extracts the probe-independent Methylated Binding Domains (MBD)-based enrichment method, which targets DNA molecules containing methylated
Comparison of Intact Parathyroid Hormone, Alkaline Phosphatase, Phosphate Levels for Diagnosing Severe Metabolic Bone Disease in Infants with Severe Bronchopulmonary Dysplasia.
Erin K Tkach et al.
American journal of perinatology, 34(12), 1199-1204 (2017-04-22)
Shingo Fukuma et al.
Scientific reports, 9(1), 11301-11301 (2019-08-07)
Achieving calcium, phosphorus, and intact parathyroid hormone (PTH) targets helps improve dialysis population outcomes. We aimed to assess the population-level associations of achievement of those targets with survival using population-attributable-fractions (PAFs). We conducted a case-cohort study using data from 8229
Moayyad E Suleiman et al.
The British journal of radiology, 91(1085), 20180032-20180032 (2018-02-06)
This work proposes the use of mammographic breast density (MBD) to estimate actual glandular dose (AGD), and assesses how AGD compares to mean glandular dose (MGD) estimated using Dance et al method. A retrospective sample of anonymised mammograms (52,405) was

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