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20835

Sigma-Aldrich

Cacodylic acid

≥99.0%

Synonym(s):

Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide

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About This Item

Linear Formula:
(CH3)2As(O)OH
CAS Number:
75-60-5
Molecular Weight:
138.00
Beilstein:
1736965
EC Number:
200-883-4
MDL number:
MFCD00002095
UNSPSC Code:
12161600
PubChem Substance ID:
57647876
NACRES:
NA.22

Assay

≥99.0%

form

solid

reaction suitability

core: arsenic
reagent type: catalyst

SMILES string

C[As](C)(O)=O

InChI

1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)

InChI key

OGGXGZAMXPVRFZ-UHFFFAOYSA-N

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Related Categories

Application

Used as herbicides.

Signal Word

Danger

Hazard Statements

H301 + H331,H350,H410

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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S Yamamoto et al.
Mutation research, 386(3), 353-361 (1997-06-01)
The modifying effects of dimethylarsinic acid (DMA), the major metabolite of ingested arsenicals in most mammals, on chemical carcinogenesis were investigated using rat in vivo models and reviewed here. In a multi-organ bioassay, rats pretreated with 5 carcinogens were administered
Erik J Tokar et al.
Toxicology letters, 209(2), 179-185 (2012-01-11)
Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking
Hua Naranmandura et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 137-146 (2012-04-28)
Arsenic is known to be a human carcinogen as well as one of the most effective drugs for treatment of patients with acute promyelocytic leukemia. The intermediate metabolites of arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)), are formed by
Kavitha Marapakala et al.
Biochemistry, 51(5), 944-951 (2012-01-20)
The enzyme As(III) S-adenosylmethionine methyltransferase (EC 2.1.1.137) (ArsM or AS3MT) is found in members of every kingdom, from bacteria to humans. In these enzymes, there are three conserved cysteine residues at positions 72, 174, and 224 in the CmArsM orthologue
Tomohiro Narukawa et al.
Journal of agricultural and food chemistry, 60(4), 1122-1127 (2012-01-10)
A monitoring test for arsenic species in white rice flour was developed and applied to flours made from 20 samples of polished rice collected from locations all over Japan. The arsenic species in white rice flour made from five samples
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