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X1251

Sigma-Aldrich

Xylazine hydrochloride

≥99.0% (HPLC), powder, sedative

Synonym(s):

2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride, 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N2S · HCl
CAS Number:
Molecular Weight:
256.79
Beilstein:
6448471
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Xylazine hydrochloride, ≥99.0% (HPLC)

Quality Level

Assay

≥99.0% (HPLC)

storage temp.

−20°C

SMILES string

Cl[H].Cc1cccc(C)c1NC2=NCCCS2

InChI

1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H

InChI key

QYEFBJRXKKSABU-UHFFFAOYSA-N

Gene Information

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Application

Xylazine hydrochloride has been used to anesthetize rats/mice.

Biochem/physiol Actions

Xylazine is used as a sedative in goats as it is safe, active and a cheap drug. It is a centrally acting drug, which exhibits muscle relaxant and analgesic properties.
α2-Adrenergic receptor agonist, sedative, muscle relaxant.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Effect of xylazine hydrochloride (Rompun(\textregistered)) on Sokoto red goats
Mohammed, A and Yelwa, HA
Small Ruminant Research, 12(1), 107-113 (1993)
Anesthesia and analgesia
The laboratory rabbit, guinea pig, hamster, and other rodents., 33-56 (2012)
Eva Wex et al.
British journal of pharmacology, 172(14), 3537-3547 (2015-04-01)
β2 -adrenoceptor agonists are widely used in the management of obstructive airway diseases. Besides their bronchodilatory effect, several studies suggest inhibitory effects on various aspects of inflammation. The aim of our study was to determine the efficacy of the long-acting

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