SAB4200190

Anti-Sumo-2/3 antibody, Rat monoclonal

clone 3H12, purified from hybridoma cell culture

• Synonym(s): Anti-HSMT3, Anti-MGC117191, Anti-SMT3 homolog 2, Anti-SMT3 suppressor of mif two 3 homolog 2, Anti-SMT3B, Anti-SMT3H2, Anti-sentrin 2, Anti-small ubiquitin-like modifier 2, Anti-small ubiquitin-related modifier 2, Anti-ubiquitin-like protein SMT3B, Monoclonal Anti-Sumo-2/3, SUMO-2/3, SUMO2/3
• MDL number: MFCD03455941
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• conjugate: unconjugated
• antibody form: purified from hybridoma cell culture
• antibody product type: primary antibodies
• clone: 3H12, monoclonal
• form: buffered aqueous solution
• mol wt: ~11 kDa
• species reactivity: mouse, rat, human
• concentration: ~1.0 mg/mL
• technique(s): immunocytochemistry: suitable; western blot: 2-4 μg/mL using HeLa cell nuclear extract
• UniProt accession no.: P55854
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SUMO3(6612) ; mouse ... Sumo3(20610) ; rat ... Sumo3(499417)

Description

General description

Monoclonal Anti-Sumo-2/3 (rat IgG2a isotype) is derived from the hybridoma 3H12 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a human SUMO3 fusion protein.

Small ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm.

Immunogen

human SUMO3 fusion protein

Application

Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and immunocytochemistry.

Biochem/physiol Actions

Small ubiquitin-like modifier (SUMO) was identified as a post-translational protein modifier.

Small ubiquitin-like modifier 3 (SUMO3) plays a vital role in enhancing cellular responses to environmental stress. It acts as a key element of the leukemogenic network in transient myeloproliferative disorder (TMD) of the newborn/acute megakaryoblastic leukaemia (AMKL).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable