777854
Tris(hydroxypropyl)phosphine
≥80%
Synonym(s):
THPP
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
Recommended Products
Assay
≥80%
form
liquid
reaction suitability
reagent type: reductant
density
1.136 g/mL at 25 °C
SMILES string
OCCCP(CCCO)CCCO
InChI
1S/C9H21O3P/c10-4-1-7-13(8-2-5-11)9-3-6-12/h10-12H,1-9H2
InChI key
YICAEXQYKBMDNH-UHFFFAOYSA-N
General description
Tris(hydroxypropyl)phosphine (THPP) is a reducing agent widely used for the reductive cleavage of disulfide bonds in small molecules in both aqueous–organic media.
Application
Tris(hydroxypropyl)phosphine can be used:
- As a reducing agent in the reduction of dehydroascorbic acid to ascorbic acid
- In the cleavage of disulfide bonds in small molecules
- As a catalyst in the conversion of polysulfides
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Biomaterials, 181, 310-317 (2018-08-11)
Tumor hypoxia is known to be one of critical factors that aggravate the tumor resistance to photodynamic therapy (PDT) in which oxygen is essential for tumor destruction. Herein, catalase, an enzyme to trigger hydrogen peroxide (H2O2) decomposition, is modified by
Pharmaceutical development and technology, 23(8), 761-770 (2017-04-01)
Dry alginate foams intended for antibacterial photodynamic therapy (aPDT) of infected wounds were prepared. aPDT is a treatment modality involving light of appropriate wavelength, oxygen and a photosensitizer (PS) to produce radicals that attack biological targets (e.g. bacteria). The hydrophobic
Nucleic acids research, 47(2), 941-952 (2018-11-22)
RNA fragments deriving from tRNAs (tRFs) exist in all branches of life and the repertoire of their biological functions regularly increases. Paradoxically, their biogenesis remains unclear. The human RNase A, Angiogenin, and the yeast RNase T2, Rny1p, generate long tRFs
Application of a New Dehydroascorbic Acid Reducing Agent in the Analysis of Vitamin C Content in Food
Molecules (Basel), 26, 6263-6263 (2021)
Tris (3-hydroxypropyl) phosphine (THPP): A mild, air-stable reagent for the rapid, reductive cleavage of small-molecule disulfides.
Bioorganic & Medicinal Chemistry Letters, 25(19), 4114-4117 (2015)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service