235237

2-Chlorophenyl phosphorodichloridate

99%

• Synonym(s): 2-Chlorophenyl dichlorophosphate
• Linear Formula: Cl₂P(O)OC₆H₄Cl
• CAS Number: 15074-54-1
• Molecular Weight: 245.43
• Beilstein: 911009
• EC Number: 239-129-4
• MDL number: MFCD00009704
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854090
• NACRES: NA.22

Properties

• Assay: 99%
• form: liquid
• refractive index: n20/D 1.538 (lit.)
• bp: 135-137 °C/12 mmHg (lit.)
• density: 1.491 g/mL at 25 °C (lit.)
• SMILES string: Clc1ccccc1OP(Cl)(Cl)=O
• InChI: 1S/C6H4Cl3O2P/c7-5-3-1-2-4-6(5)11-12(8,9)10/h1-4H
• InChI key: VLDPXPPHXDGHEW-UHFFFAOYSA-N

Description

Application

2-Chlorophenyl phosphorodichloridate has been used in the preparation of:

• mononucleotide building blocks
• oligonucleotides and oligonucleotide phosphorothioates in solution

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 221.0 °F - closed cup
• Flash Point(C): 105 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves