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  • Tributylphosphine-catalyzed cycloaddition of aziridines with carbon disulfide and isothiocyanate.

Tributylphosphine-catalyzed cycloaddition of aziridines with carbon disulfide and isothiocyanate.

The Journal of organic chemistry (2008-10-24)
Jing-Yu Wu, Zhi-Bin Luo, Li-Xin Dai, Xue-Long Hou
ABSTRACT

Aziridines underwent cyclization reaction with carbon disulfide and isothiocyanate in the presence of organophosphine to afford thiazolidinone derivatives in good to high yields. The mechanistic study revealed that organophosphine serves as a catalyst in the reaction.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Tributylphosphine, ≥93.5% (Tri-N-butylphosphine, GC)
Sigma-Aldrich
Tributylphosphine, mixture of isomers, 97%
Sigma-Aldrich
Tri-n-butylphosphine, 97%
Sigma-Aldrich
Tributylphosphine solution, 200 mM (in N-methyl-2-pyrrolidinone), liquid
Sigma-Aldrich
Tri-n-butylphosphine, 99%