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Key Documents

AB9680

Sigma-Aldrich

Anti-GABA A Receptor β 1 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GABRB1(2560)

Specificity

GABAA Receptor beta 1 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor beta 1 subunit in lysates from rat cerebellum and cortex.

Immunogen

Fusion protein from the Cytosolic loop of rat the GABAA Receptor beta 1 subunit.

Application

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-GABA A Receptor β 1 Antibody is validated for use in WB for the detection of GABA A Receptor β 1.
Western blot: 1:1,000.

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: AB5451

Physical form

Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Storage and Stability

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alejandra Cabello-Arreola et al.
Genes, 11(3) (2020-03-04)
Suicide is a major public health concern; nevertheless, its neurobiology remains unknown. An area of interest in suicide research is the dorsolateral prefrontal cortex (DLPFC). We aimed to identify altered proteins and potential biological pathways in the DLPFC of individuals
S H Fatemi et al.
Translational psychiatry, 3, e303-e303 (2013-09-12)
There is abundant evidence that dysfunction of the γ-aminobutyric acid (GABA)ergic signaling system is implicated in the pathology of schizophrenia and mood disorders. Less is known about the alterations in protein expression of GABA receptor subunits in brains of subjects
S Hossein Fatemi et al.
Synapse (New York, N.Y.), 71(7) (2017-03-21)
Schizophrenia and bipolar disorder are complex psychiatric disorders that affect millions of people worldwide. Evidence from gene association and postmortem studies has identified abnormalities of the gamma-aminobutyric acid (GABA) signaling system in both disorders. Abnormal GABAergic signaling and transmission could
S Hossein Fatemi et al.
Journal of autism and developmental disorders, 40(6), 743-750 (2010-01-13)
We have shown altered expression of gamma-aminobutyric acid A (GABA(A)) and gamma-aminobutyric acid B (GABA(B)) receptors in the brains of subjects with autism. In the current study, we sought to verify our western blotting data for GABBR1 via qRT-PCR and

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