N-070

Norquetiapine hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): Norquetiapine hydrochloride solution
• Empirical Formula (Hill Notation): C₁₇H₁₇N₃S · HCl
• CAS Number: 753475-15-9
• Molecular Weight: 331.86
• EC Number: 200-659-6
• MDL number: MFCD09835377
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol (as free base)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [H]Cl.C12=CC=CC=C1N=C(N3CCNCC3)C4=C(C=CC=C4)S2
• InChI: 1S/C17H17N3S.ClH/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15;/h1-8,18H,9-12H2;1H
• InChI key: MJPARFLICDXWJT-UHFFFAOYSA-N

Description

General description

Norquetiapine is a primary active metabolite of quetiapine, marketed as the atypical antipsychotic Seroquel^® for the treatment of depression, bipolar disorder, and schizophrenia. It maintains most of the pharmacological effects of quetiapine with potencies similar to the parent drug.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Seroquel is a registered trademark of Astrazeneca UK

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup