- Isolation and characterization of a human novel RAB (RAB39B) gene.
Isolation and characterization of a human novel RAB (RAB39B) gene.
Cytogenetic and genome research (2002-11-20)
H Cheng, Y Ma, X Ni, M Jiang, L Guo, K Ying, Y Xie, Y Mao
PMID12438742
ABSTRACT
Rab proteins are small-molecular-weight GTPases that control vesicular trafficking in eukaryotic cells. During the large-scale sequencing analysis of a human fetal brain cDNA library, we isolated a cDNA clone encoding a novel Rab protein, which showed 74.2% identity with previously isolated Rab39A at the amino acid level. RAB39B was expressed in a variety of human tissues and located in human chromosome Xq28. It consisted of two exons spanning 3764 bp of human genomic DNA.