- Copper-catalyzed [4 + 1] cycloadditions of alpha,beta-acetylenic ketones with diazoacetates to form trisubstituted furans.
Copper-catalyzed [4 + 1] cycloadditions of alpha,beta-acetylenic ketones with diazoacetates to form trisubstituted furans.
The Journal of organic chemistry (2007-11-29)
Lian-Biao Zhao, Zheng-Hui Guan, Yao Han, Yong-Xin Xie, Sheng He, Yong-Min Liang
PMID18041850
ABSTRACT
Copper-catalyzed [4 + 1] cycloaddition reaction of alpha,beta-acetylenic ketones with alpha-diazo esters offers an efficient, direct route to highly substituted furans. The reaction conditions and the scope of the process are examined, and a possible mechanism is proposed.
MATERIALS
Product Number
Brand
Product Description