MABF846

Anti-LAG3 Antibody, clone C9B7W (Azide Free)

• Synonym(s): LAG3|Lymphocyte activation gene 3 protein|LAG-3|CD223
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rat
• Quality Level: 300
• clone: monoclonal
• species reactivity: mouse
• technique(s): activity assay: suitable; flow cytometry: suitable

Description

General description

Lymphocyte-activation gene 3 (LAG3), also known as cluster of differentiation 223 (CD223), is an immunoglobulin superfamily (IgSF) type I membrane protein encoded by the LAG3 gene in human. LAG3 is expressed in human activated T and NK cells and involved lymphocyte activation by functioning as a ligand for major histocompatibility complex (MHC) class II molecules.

Immunogen

Recombinant protein corresponding to within the extracellular D2 domain of mouse LAG3.

Application

Anti-LAG3 Antibody, clone C9B7W (Azide Free) is an antibody against LAG3 for use in Flow Cytometry, Activity Assay.

Flow Cytometry Analysis: A representative lot detected LAG3 in TILs from B16 and MC38 mice (Woo, S., et al. (2011). Cancer Research. 72(4):917-927).
Flow Cytometry Analysis: A representative lot detected LAG3 in activated T cells from CD223-/- and CD2

Quality

Evaluated by Flow Cytometry in Staph enterotoxin B treated mouse splenocyte.

Flow Cytometry Analysis: 1.0 ug of this antibody detected LAG3 in Staph enterotoxin B treated mouse splenocyte.

Other Notes

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial