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323527

Sigma-Aldrich

Selenium tetrachloride

Synonym(s):

Selenium (Ⅳ) chloride

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About This Item

Linear Formula:
SeCl4
CAS Number:
10026-03-6
Molecular Weight:
220.77
EC Number:
233-053-5
MDL number:
MFCD00011225
UNSPSC Code:
12352302
PubChem Substance ID:
24859372
NACRES:
NA.23

form

powder or crystals

concentration

35.0-36.5% Se (after reduction with sulphite, gravimetric)

density

2.6 g/mL at 25 °C (lit.)

SMILES string

Cl[Se](Cl)(Cl)Cl

InChI

1S/Cl4Se/c1-5(2,3)4

InChI key

LNBXMNQCXXEHFT-UHFFFAOYSA-N

Signal Word

Danger

Hazard Statements

H301 + H331,H373,H410

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Brenda Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(13), 5679-5686 (2002-07-05)
It has been proposed that prostaglandin (PG) D(2) induces physiological sleep in mammals by acting on sleep centers located in the anterior hypothalamus. In fetal sheep, definitive rapid-eye-movement and non-rapid-eye-movement sleep states appear at approximately 125 d gestation (term is
H Matsumura et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(20), 9046-9050 (1991-10-15)
Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor in rats, and SeCl4 and Na2SeO3 recently have been shown to inhibit the PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2) activity of rat brain. The effect of these selenium
F Islam et al.
Archives of biochemistry and biophysics, 289(1), 161-166 (1991-08-15)
Various inorganic selenocompounds dose-dependently inhibited the rat brain prostaglandin (PG) D synthase, both in the purified enzyme preparation and in the crude brain supernatant. All of the quadrivalent selenium compounds tested had a very limited range of IC50 values in
R Takahata et al.
Brain research, 623(1), 65-71 (1993-09-24)
Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor. Biosynthesis of PGD2 is catalyzed by PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2), the activity of which is inhibited by inorganic selenium compounds such as SeCl4 and Na2SeO3. We
Sun-Chol Yu et al.
Organic & biomolecular chemistry, 8(4), 828-834 (2010-02-06)
Low molecular weight seleno-organic compounds exhibit glutathione peroxidase (GPx)-like activity; the well-known compound ebselen is being used in clinical trials as a stroke medication. Here, we describe the facile one-step synthesis of novel 5-selenized salicylic acid derivatives using selenium tetrachloride.
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