TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Synonyms:
ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3
Species:
Human TCIRG1 (10312), Mouse Tcirg1 (27060), Rat Tcirg1 (293650), Zebrafish tcirg1 (100003139), chicken TCIRG1 (395472), domestic cat TCIRG1 (101083709), dog TCIRG1 (483691), naked mole-rat Tcirg1 (101720677), sheep TCIRG1 (101113184), Domestic Rabbit TCIRG1 (100008819) ...More
UniProtKB ID:
Gene ID:
- Human(10312) Summary: Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, Jul 2008]
- Mouse(27060) T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
- Rat(293650) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- Zebrafish(100003139) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- chicken(395472) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- domestic cat(101083709) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- dog(483691) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- naked mole-rat(101720677) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- sheep(101113184) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- Domestic Rabbit(100008819) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- domestic guinea pig(100712820) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- cow(513684) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
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