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Merck

MYH7

myosin, heavy chain 7, cardiac muscle, beta

Synonyms:
CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM
Species:
Human MYH7 (4625), Mouse Myh7 (140781), Rat Myh7 (29557), Domestic Rabbit MYH7 (100101566), dog MYH7 (403807), chicken MYH7 (395350), Zebrafish myh7 (100534858), cow MYH7 (282714), Horse MYH7 (791234), domestic cat MYH7 (101096736) ...More
UniProtKB ID:
P12883, A2TDB6, B6D424, Q14836, Q14837, Q14904, Q16579, Q2M1Y6
Gene ID:
  • Human(4625) Summary: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008]
  • Mouse(140781) myosin, heavy polypeptide 7, cardiac muscle, beta
  • Rat(29557) myosin, heavy chain 7, cardiac muscle, beta
  • Domestic Rabbit(100101566) myosin, heavy chain 7, cardiac muscle, beta
  • dog(403807) myosin, heavy chain 7, cardiac muscle, beta
  • chicken(395350) myosin, heavy chain 7, cardiac muscle, beta
  • Zebrafish(100534858) myosin, heavy chain 7, cardiac muscle, beta
  • cow(282714) myosin, heavy chain 7, cardiac muscle, beta
  • Horse(791234) myosin, heavy chain 7, cardiac muscle, beta
  • domestic cat(101096736) myosin, heavy chain 7, cardiac muscle, beta
  • naked mole-rat(101707190) myosin, heavy chain 7, cardiac muscle, beta
  • domestic guinea pig(100727138) myosin, heavy chain 7, cardiac muscle, beta

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
MABT849
Anti-Myosin 7 (MYH7) Antibody, clone 4B51E8, clone 4B51E8, from rat,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
MAB1548
Anti-Myosin Antibody, heavy chain β, culture supernatant, clone 5B9 (2C8), Chemicon®,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA001239
Anti-MYH7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB4200670
Anti-Myosin (Skeletal, Slow) antibody, Mouse monoclonal, clone NOQ7.5.4D, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, chicken, feline, goat, guinea pig, hamster, human, mouse, pig, rabbit, rat, sheep
Application
immunohistochemistry
western blot
SAB5702539
Anti-Myosin heavy chain Antibody, clone 6V0G1, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU205191
MISSION® esiRNA, targeting mouse Myh7,
Species
mouse
EHU123891
MISSION® esiRNA, targeting human MYH7,
Species
human