Skip to Content
Merck

MXD1

MAX dimerization protein 1

Synonyms:
BHLHC58, MAD, MAD1
Species:
UniProtKB ID:
Gene ID:
  • Human(4084) Summary: This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(17119) MAX dimerization protein 1
  • Rat(362391) max dimerization protein 1
  • domestic guinea pig(100726750) MAX dimerization protein 1
  • Zebrafish(570082) MAX dimerization protein 1
  • naked mole-rat(101697362) MAX dimerization protein 1
  • cow(514626) MAX dimerization protein 1
  • chicken(426299) MAX dimerization protein 1
  • sheep(101106754) MAX dimerization protein 1
  • domestic cat(101095166) MAX dimerization protein 1
  • dog(612631) MAX dimerization protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MXD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Mxd1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-MXD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-MXD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, human, mouse, rat
Application
western blot

Proteins

Product Number
Description
Species
MAX dimerization protein 1 (MAD) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MXD1,
Species
human
MISSION® esiRNA, targeting mouse Mxd1,
Species
mouse