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Merck

LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

Synonyms:
CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10
Species:
Human LILRB2 (10288), dog LILRB2 (484309)
UniProtKB ID:
Q8N423, O75017, Q8NHJ7, Q8NHJ8
Gene ID:
  • Human(10288) Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • dog(484309) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1408749
Anti-LILRB2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
WH0010288M1
Monoclonal Anti-LILRB2 antibody produced in mouse, clone 1D4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ABN1023
Anti-LILRB2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU147581
MISSION® esiRNA, targeting human LILRB2,
Species
human