JAK3
Janus kinase 3
Synonyms:
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Species:
Human JAK3 (3718), Mouse Jak3 (16453), Rat Jak3 (25326), domestic guinea pig Jak3 (100713900), sheep JAK3 (101112816), domestic cat JAK3 (101092339), domestic cat JAK3 (493680), Horse JAK3 (100147451), cow JAK3 (538276), dog JAK3 (610004) ...More
UniProtKB ID:
Gene ID:
- Human(3718) Summary: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
- Mouse(16453) Janus kinase 3
- Rat(25326) Janus kinase 3
- domestic guinea pig(100713900) Janus kinase 3
- sheep(101112816) Janus kinase 3
- domestic cat(101092339) Janus kinase 3
- domestic cat(493680) Janus kinase 3
- Horse(100147451) Janus kinase 3
- cow(538276) Janus kinase 3
- dog(610004) Janus kinase 3
- chicken(395845) Janus kinase 3
- Zebrafish(561370) Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- naked mole-rat(101715472) Janus kinase 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-JAK3 antibody produced in mouse, clone 2A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-phospho-JAK3 (pTyr785) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-JAK3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human, mouse, pig, rat
Application
western blot
Anti-JAK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-p-JAK3 (Tyr980/981) Antibody, clone 2D9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
canine, human, monkey, porcine
Application
affinity binding assay
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Proteins
Product Number
Description
Species
Jak3 Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
Species
human
JAK3 (781-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human