GSTM3
glutathione S-transferase mu 3 (brain)
Synonyms:
GST5, GSTB, GSTM3-3, GTM3
Species:
Human GSTM3 (2947), Mouse Gstm3 (14864), Rat Gstm3 (57298), naked mole-rat Gstm3 (101708562), cow GSTM3 (615507), domestic cat GSTM3 (100169963), dog GSTM3 (479911), Zebrafish gstm3 (568744)
UniProtKB ID:
Gene ID:
- Human(2947) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
- Mouse(14864) glutathione S-transferase, mu 3
- Rat(57298) glutathione S-transferase mu 3
- naked mole-rat(101708562) glutathione S-transferase mu 3 (brain)
- cow(615507) glutathione S-transferase mu 3 (brain)
- domestic cat(100169963) glutathione S-transferase mu 3 (brain)
- dog(479911) glutathione S-transferase mu 3 (brain)
- Zebrafish(568744) glutathione S-transferase M3 (brain)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GSTM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Cell Lines
Product Number
Description
Species