DMP1
dentin matrix acidic phosphoprotein 1
Synonyms:
ARHP, ARHR, DMP-1
Species:
Human DMP1 (1758), Mouse Dmp1 (13406), Rat Dmp1 (25312), Thale Cress DMP1 (821706), domestic guinea pig Dmp1 (100732102), naked mole-rat Dmp1 (101725040), sheep DMP1 (100861441), sheep DMP1 (101123558), domestic cat DMP1 (101095652), cow DMP1 (281118) ...More
UniProtKB ID:
Gene ID:
- Human(1758) Summary: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13406) dentin matrix protein 1
- Rat(25312) dentin matrix acidic phosphoprotein 1
- Thale Cress(821706) DUF679 domain membrane protein 1
- domestic guinea pig(100732102) dentin matrix acidic phosphoprotein 1
- naked mole-rat(101725040) dentin matrix acidic phosphoprotein 1
- sheep(100861441) dentin matrix acidic phosphoprotein 1
- sheep(101123558) dentin matrix acidic phosphoprotein 1
- domestic cat(101095652) dentin matrix acidic phosphoprotein 1
- cow(281118) dentin matrix acidic phosphoprotein 1
- chicken(404539) dentin matrix acidic phosphoprotein 1
- dog(487849) dentin matrix acidic phosphoprotein 1
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ELISA
Product Number
Description
Species
Human DMP1 / Dentin Matrix Acidic Phosphoprotein 1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DMP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-DMP1 antibody produced in mouse, clone 1D4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-DMP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-DMP-1 (CT) Antibody, clone 8G10.3, clone 8G10.3, from mouse,
Species Reactivity
human, mouse, rat
Application
dot blot
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species