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Merck

CCL22

chemokine (C-C motif) ligand 22

Synonyms:
ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
Species:
UniProtKB ID:
Gene ID:
  • Human(6367) Summary: This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Jul 2008]
  • Mouse(20299) chemokine (C-C motif) ligand 22
  • Rat(117551) chemokine (C-C motif) ligand 22
  • dog(100686212) chemokine (C-C motif) ligand 22
  • naked mole-rat(101699782) chemokine (C-C motif) ligand 22
  • domestic guinea pig(100716085) chemokine (C-C motif) ligand 22
  • domestic cat(101091326) chemokine (C-C motif) ligand 22
  • cow(616996) chemokine (C-C motif) ligand 22
  • sheep(101123141) chemokine (C-C motif) ligand 22

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Mouse Ccl22 / C-C Motif Chemokine 22 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
mouse
Human MDC / CCL22 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-CCL22 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Macrophage-Derived Chemokine antibody produced in chicken, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
MDC (67 aa) (CCL22) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCL22,
Species
human