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Merck

CACNB1

calcium channel, voltage-dependent, beta 1 subunit

Synonyms:
CAB1, CACNLB1, CCHLB1
Species:
UniProtKB ID:
Gene ID:
  • Human(782) Summary: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12295) calcium channel, voltage-dependent, beta 1 subunit
  • Rat(50688) calcium channel, voltage-dependent, beta 1 subunit
  • Zebrafish(436925) calcium channel, voltage-dependent, beta 1 subunit
  • cow(327703) calcium channel, voltage-dependent, beta 1 subunit
  • sheep(101122960) calcium channel, voltage-dependent, beta 1 subunit
  • domestic cat(101089057) calcium channel, voltage-dependent, beta 1 subunit
  • domestic guinea pig(100721141) calcium channel, voltage-dependent, beta 1 subunit
  • naked mole-rat(101714578) calcium channel, voltage-dependent, beta 1 subunit
  • dog(491030) calcium channel, voltage-dependent, beta 1 subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CACNB1 antibody produced in mouse, clone 1G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CACNB1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, human, rabbit
Application
immunohistochemistry
western blot
Anti-CACNB1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-CACNB1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CACNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Bepridil hydrochloride, powder,
Species
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CACNB1,
Species
human
MISSION® esiRNA, targeting mouse Cacnb1,
Species
mouse