ADSL
adenylosuccinate lyase
Synonyms:
AMPS, ASASE, ASL
Species:
Human ADSL (158), Mouse Adsl (11564), Rat Adsl (315150), dog ADSL (474499), Zebrafish adsl (334431), naked mole-rat Adsl (101719217), chicken ADSL (396540), cow ADSL (510949), domestic cat ADSL (101085644), sheep ADSL (101108120)
UniProtKB ID:
Gene ID:
- Human(158) Summary: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11564) adenylosuccinate lyase
- Rat(315150) adenylosuccinate lyase
- dog(474499) adenylosuccinate lyase
- Zebrafish(334431) adenylosuccinate lyase
- naked mole-rat(101719217) adenylosuccinate lyase
- chicken(396540) adenylosuccinate lyase
- cow(510949) adenylosuccinate lyase
- domestic cat(101085644) adenylosuccinate lyase
- sheep(101108120) adenylosuccinate lyase
- domestic guinea pig(100713101) adenylosuccinate lyase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ADSL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ADSL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot