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Merck

ADH5

alcohol dehydrogenase 5 (class III), chi polypeptide

Synonyms:
ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR
Species:
UniProtKB ID:
Gene ID:
  • Human(128) Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
  • Mouse(11532) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Rat(100145871) alcohol dehydrogenase 5 (class III), chi polypeptide
  • domestic guinea pig(100719427) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Domestic Rabbit(100009307) alcohol dehydrogenase 5 (class III), chi polypeptide
  • sheep(101112223) alcohol dehydrogenase 5 (class III), chi polypeptide
  • cow(505515) alcohol dehydrogenase 5 (class III), chi polypeptide
  • domestic cat(101101307) alcohol dehydrogenase 5 (class III), chi polypeptide
  • dog(609781) alcohol dehydrogenase 5 (class III), chi polypeptide
  • chicken(422705) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Zebrafish(116517) alcohol dehydrogenase 5
  • naked mole-rat(101717353) alcohol dehydrogenase 5 (class III), chi polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ADH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ADH5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-ADH5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Kits

Product Number
Description
Species
Alcohol Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
rat, mouse, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADH5,
Species
human
MISSION® esiRNA, targeting mouse Adh5,
Species
mouse