ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

Synonyms:

ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1

Species:

Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), domestic guinea pig Abcg2 (100723442), domestic cat ABCG2 (101094017), chicken ABCG2 (423767), dog ABCG2 (478472), Horse ABCG2 (100034164), cow ABCG2 (536203), sheep ABCG2 (780508) ...More

UniProtKB ID:

Q9UNQ0, A0A1W3, A8K1T5, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64

Gene ID:

Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2
Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2

Products (13)
Peer Reviewed Papers (1,293)

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