RAB0629

Human GDF2 / Growth/Differentiation Factor 2 ELISA Kit

• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type plasma; sample type cell culture supernatant(s); sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 32 pg/mL; standard curve range: 32.77-8000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... GDF2(2658)

Description

General description

The growth differentiation factor 2 (GDF2) gene encodes for bone morphogenic protein 9 (BMP9). GDF2, also known as BMP9, belongs to the BMP family. The GDF2 gene is mapped on the human chromosome at 10q11.22. GDF2/BMP9 protein regulates angiogenesis, modulating tumorigenesis, inhibiting hepatic glucose production, and maintaining basal forebrain cholinergic neurons. It is implicated in the pathogenesis of pulmonary arterial hypertension. Mutations in the GDF2 gene are associated with hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant vascular disorder. The antibody pair provided in this kit recognizes human growth/differentiation factor 2.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit Components Also Available Separately

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Statements: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable