I8782

Interferon αA from mouse

≥95%, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture

• Synonym(s): IFN-αA
• MDL number: MFCD02253032
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: mouse
• Quality Level: 200
• recombinant: expressed in E. coli
• Assay: ≥95%
• form: buffered aqueous solution
• mol wt: 20 kDa
• technique(s): cell culture | mammalian: suitable
• color: colorless
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: mouse ... Ifna3(110218)

Description

Biochem/physiol Actions

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes) and ruminant embryos (τ subtypes). Interferon induces a variety of effects on target cells including antiviral, antiproliferative and immunomodulatory activities.

Packaging

Minimum 1x10⁵ units/vial.

Physical form

Solution in phosphate buffered saline containing 0.1% bovine serum albumin.

Analysis Note

The biological activity is determined in the cytopathic effect inhibition assay using mouse L929 cells with encephalomyocarditis virus. The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. The units are determined with respect to NIH international standard reference for mouse interferon α.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves