H7660
Heregulin-β1 (EGF Domain) human
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
Synonym(s):
HRG-β1
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About This Item
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
<0.50 ng/mL
mol wt
predicted mol wt 8 kDa
packaging
pkg of 10 and 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
color
white
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... NRG1(3084)
Biochem/physiol Actions
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.
Analysis Note
The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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