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B5524

Supelco

Benzydamine hydrochloride

analytical standard

Synonym(s):

1-Benzyl-3-(3-[dimethylamino]propoxy)-1H-indazole

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O · HCl
CAS Number:
132-69-4
Molecular Weight:
345.87
EC Number:
205-076-0
MDL number:
MFCD00078957
UNSPSC Code:
41116107
PubChem Substance ID:
329773263
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13

InChI

1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

InChI key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000257025
0000254328
035K0816
124K1460
114K1229

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F Capolongo et al.
Journal of veterinary pharmacology and therapeutics, 33(4), 341-346 (2010-07-22)
Benzydamine (BZ), a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, is metabolized in human, rat, cattle and rabbit to a wide range of metabolites. One of the main metabolites, BZ
Takeshi Sawada et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(5), 526-535 (2019-09-07)
1. Immunodeficient chimeric mice with humanised liver have been useful in predicting total clearance values of drugs in humans. However, their usefulness may currently be limited for specific compounds with interspecies differences.2. In vivo total clearance and in vitro hepatic
Ali Fuat Erciyas et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(10), 2577-2580 (2010-07-06)
In this study, genotoxicity of two mouthwash products (chlorexidin, benzidamine-HCl) were investigated in the Drosophila Wing-Spot Test which makes use of the wing cell markers multiple wing hairs (mwh) and flare (flr) and detects both mitotic recombination and various types
Yildiz Yilmaz et al.
Xenobiotica; the fate of foreign compounds in biological systems, 49(5), 503-512 (2018-04-26)
The expression of flavin-containing monooxygenase (FMO) varies extensively between human and commonly used preclinical species such as rat and mouse. The aim of this study was to investigate the pulmonary FMO activity in rat using benzydamine. Furthermore, the contribution of
Koray Soygun et al.
The journal of advanced prosthodontics, 9(3), 200-207 (2017-07-07)
In this study, three bioceramic materials, [IPS Empress CAD (Ivoclar), IPS e.max CAD (Ivoclar), and Lava Ultimate CAD (3M ESPE)] were treated with three commercial mouthrinses [Listerine, Tantum Verde, and Klorhex]; and changes in colour reflectance and surface roughness values
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