Skip to Content
Merck
All Photos(1)

Key Documents

746614

Sigma-Aldrich

SAM Formation reagent for carboxylic acid terminated monolayer on gold surface

Synonym(s):

Carboxylic acid-SAM

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352103
NACRES:
NA.23

form

liquid

storage temp.

2-8°C

General description

Carboxylic acid- SAM is an acid terminated self-assembled monolayer on the surface of gold, which is mainly utilized to immobilize the surface atoms. The SAM film formed has a high degree of molecular orientation. This reagent is majorly utilized in surface science, biomineralization, and sensor based applications.

Application

Used to prepare carboxylic acid- terminated self-assembled monolayers (SAMs) on gold surfaces as biosensors detected by QCM (Quartz Crystal Microbalance), SPR (Surface Plasmon Resonance), and electrochemical analysis.
Coupled with carboxyl group activation method using NHS/WSC, carboxylic acid-SAM can be used as an interface to immobilize proteins or peptides and other ligands on gold surfaces.
This SAM Formation Reagent presents less non-specific binding than those commonly prepared with carboxylic acid-SAM.
Storage: Keep tightly closed; packed under Nitrogen gas; store in cooler (0~5 °C); dark and dry place.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Influence of gold substrate topography on the voltammetry of cytochrome c adsorbed on carboxylic acid terminated self-assembled monolayers.
Leopold MC and Bowden EF
Langmuir, 18(6), 2239-2245 (2002)
Preparation, modification, and crystallinity of aliphatic and aromatic carboxylic acid terminated self-assembled monolayers.
Arnold R, et al.
Langmuir, 18(10), 3980-3992 (2002)
Effects of self-assembled monolayers on amperometric glucose biosensors based on an organic-inorganic hybrid system
Wang, Huihui;
Sensors and Actuators B, Chemical, 168, 249-255 (2012)
J Christopher Ball et al.
Analytical chemistry, 75(24), 6932-6937 (2003-12-13)
The enzyme beta-galactosidase has been covalently immobilized onto a gold-coated magnetoelastic film via a self-assembled monolayer (SAM) of omega-carboxylic acid alkylthiol. Use of magnetoelastic transduction allows for the wireless monitoring of enzymatic activity through the associated change in the frequency

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service