- Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells.
Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells.
Scientific reports (2017-09-06)
Yuan Zhang, Xianliang Ke, Caishang Zheng, Yan Liu, Li Xie, Zhenhua Zheng, Hanzhong Wang
PMID28871120
摘要
Enterovirus 71 (EV71) is a major pathogen of hand, foot, and mouth disease (HFMD). To date, no antiviral drug has been approved to treat EV71 infection. Due to the essential role that EV71 3 C protease (3C
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