- Comparative in vitro and in vivo taste assessment of liquid praziquantel formulations.
Comparative in vitro and in vivo taste assessment of liquid praziquantel formulations.
International journal of pharmaceutics (2017-07-12)
Magdalena Münster, Abeer H A Mohamed-Ahmed, Laura I Immohr, Corinna Schoch, Carsten Schmidt, Catherine Tuleu, Jörg Breitkreutz
PMID28689966
摘要
The taste of pharmaceuticals strongly affects the compliance of patients. This study investigated the applicability of the electronic tongue and rodent brief-access taste aversion (BATA) model for the bitter compound praziquantel (PZQ) and taste masked liquid formulations for PZQ. In a comparative study maltodextrin (MD) Kleptose