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Merck

Presence of an H

European journal of drug metabolism and pharmacokinetics (2015-12-03)
Miki Fukao, Eri Kondo, Hiroki Nishino, Ryutaro Hattori, Asuka Horie, Yukiya Hashimoto
摘要

We have recently found an H We investigated the uptake and efflux of quinidine in MDCK cells. The uptake of 100 µM quinidine into MDCK cells was decreased by acidification of extracellular pH or alkalization of intracellular pH. In addition, the uptake of quinidine was highly temperature sensitive, but was extracellular Na The present findings suggested that the renal new antiport system is involved in the bidirectional membrane transport of quinidine in MDCK cells.

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奎尼丁 盐酸盐 一水合物, technical grade