Asymmetric hydrogenation of aryl ketones mediated by a copper catalyst.

Asymmetric hydrogenation of aryl ketones mediated by a copper catalyst.

Organic letters (2007-03-29)

Hideo Shimizu, Daisuke Igarashi, Wataru Kuriyama, Yukinori Yusa, Noboru Sayo, Takao Saito

摘要

[reaction: see text] A novel asymmetric hydrogenation protocol using a copper catalyst is reported. A Cu(I) complex in the presence of nonracemic BDPP hydrogenates aryl ketones with moderate to high enantioselectivity.