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Merck
  • Prognostic value of type XXII and XXIV collagen mRNA expression in head and neck cancer patients.

Prognostic value of type XXII and XXIV collagen mRNA expression in head and neck cancer patients.

Molecular and clinical oncology (2014-03-22)
Kiyoshi Misawa, Takeharu Kanazawa, Atsushi Imai, Shiori Endo, Daiki Mochizuki, Hirofumi Fukushima, Yuki Misawa, Hiroyuki Mineta
PMID24649348
摘要

Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer, affecting ~500,000 individuals worldwide annually. Collagen is the major constituent of the extracellular matrix component in tumors and plays a crucial role in tumor development. The aim of this study was to determine the mRNA expression of type XXI, XXII, XXIII and XXIV α1 collagen (