Relative resistance of rabbits to MPTP neurotoxicity.

Relative resistance of rabbits to MPTP neurotoxicity.

Molecular and chemical neuropathology (1995-06-01)

N Lermontova, O Drany, D Dobrota, V Mezesova, V Lombardi, S Bachurin

摘要

The neurotoxic actions of MPTP and its 4-(O-tolyl) analog (2'-Me-MPTP) on two breeds of rabbits were investigated. MPTP, but not 2'-Me-MPTP, causes a reduction (about 40%) in striatal dopamine content in rabbits of the "little silver-black" breed. The dopamine content of striata of "chinchilla" rabbits was not affected by either agent.

材料

货号

品牌

产品描述

M103

Sigma-Aldrich

1-甲基-4-(2′-甲基苯基)-1,2,3,6-四氢吡啶盐酸盐, solid