- Aryl-heteroaryl derivatives as novel wake-promoting agents.
Aryl-heteroaryl derivatives as novel wake-promoting agents.
Chemical biology & drug design (2012-11-01)
Brigitte Lesur, Yin G Lin, Val R Marcy, Lisa D Aimone, John Gruner, Edward R Bacon, Sankar Chatterjee
PMID23110414
摘要
In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.
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Supelco
Modafinil solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®