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Merck

Method for activation and recycling of trityl resins.

The Journal of organic chemistry (2012-07-20)
Itedale Namro Redwan, Morten Grøtli
摘要

This note describes a rapid and mild strategy for the loading of alcohols and anilines onto a polystyrene triphenylmethyl (trityl) resin. High loadings were obtained in a matter of minutes by treating resin-bound trityl chloride with triethyloxonium tetrafluoroborate followed by alcohols or anilines. Yields were comparable or better than known literature methods. Recycling of the recovered resin was also possible using the developed method.

材料
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产品描述

Sigma-Aldrich
三苯基氯甲烷, 97%
Sigma-Aldrich
三乙基氧鎓四氟硼酸盐 溶液, 1.0 M in methylene chloride
Sigma-Aldrich
三乙基氧鎓四氟硼酸盐, ≥97.0% (T)
Sigma-Aldrich
三苯基氯甲烷, purum, ≥97.0% (HPLC), ≥97.0% (AT)